Why Estrogen Matters to Your Skin- Youthful Skin in Menopause

As estrogen levels decline during menopause, noticeable changes occur in the skin. Many women experience increased dryness, loss of elasticity, fine lines, and slower wound healing. This is because estrogen plays a key role in maintaining skin thickness, hydration, and collagen production. Understanding these changes empowers women to take proactive steps in preserving their skin health.

How Estrogen Affects the Skin

Estrogen influences multiple aspects of skin function, including:

• Collagen Production: Collagen provides structure and firmness to the skin. Studies show that postmenopausal women experience a 2% decline in skin collagen per year, leading to thinner and more fragile skin.

• Moisture Retention: Estrogen helps the skin maintain hydration by increasing hyaluronic acid production. Reduced estrogen levels contribute to dryness and dullness.

• Wound Healing & Barrier Function: Declining estrogen can slow the skin’s ability to heal and fight environmental damage.

• Elasticity & Wrinkle Formation: With less estrogen, the skin loses elasticity, leading to sagging and deeper wrinkles.

Treatment Options for Estrogen-Deficient Skin

The good news? There are effective treatments available to combat these changes. Here’s what some research is examining:

1️⃣ Hormone Therapy (HT)

There is some research that supports topical estrogen creams containing estradiol (E2) or estriol (E3) can significantly improve skin elasticity, moisture levels, and wrinkle depth reduction. A six-month study found that estrogen-based creams increased collagen levels, reducing wrinkles by up to 61-100%. There has not been a great deal of research on topical estrogen and skin. Many companies have begun selling it however, we are not quite ready to advocate this. If you wish to try, share with us your thoughts!

Here is some of the research:

A Double-Blind Randomized Pilot Study Evaluating the Safety and Efficacy of Topical MEP in the Facial Appearance Improvement of Estrogen Deficient Females

Difference Between Sun-Protected and Photodamaged Human Skin In Vivo

Treatment of skin aging with topical estrogens

2️⃣ Phytoestrogens (Plant-Based Estrogen Alternatives)

For women who prefer hormone-free options, plant-derived compounds known as phytoestrogens mimic estrogen’s effects on the skin. Two promising ingredients include:

• Resveratrol (4AR): A powerful antioxidant found in grapes and red wine that stimulates collagen production.

• Equol: An isoflavonoid derived from soy that activates estrogen receptors in the skin, promoting elasticity and hydration.

More research is required on phytoestrogens and if they can directly impact the skin and how much is required to be consumed for any noticeable impacts.

3️⃣ Skincare & Lifestyle Adjustments

Even without hormonal treatments, you can support your skin by:

✅Hydration is your first line of defense, staying hydrated is key

✅ Using hydrating serums with hyaluronic acid & ceramides

✅ Applying broad-spectrum SPF daily to protect collagen

✅ Eating collagen-boosting foods like leafy greens, berries, and protein-rich meals

✅ Staying hydrated and avoiding excess alcohol or smoking.

Take Control of Your Skin Health

Menopause doesn’t mean giving up on glowing, youthful skin. With the right knowledge and treatments—whether hormonal, botanical, or lifestyle-based—you can maintain radiance and resilience at any age. What steps are you taking to care for your skin today?

Check out our podcast with NYC Dermatologist Dr. Doris Day on keeping your skin youthful!.